Here at the Alliance for Aging Research we are huge fans of the African naked mole rat. Now, why would anyone love a 4-inch squinty-eyed hairless wrinkled rodent with buck teeth?
Let's put it this way: How would you like to live five times the normal human lifespan with rock-solid immunity to cancer and arteries smooth and supple as a teenager; and when you reach the end of an incredibly long life, have death come without a single day of sickness or disability? Those are a few of the tricks that come naturally to a critter that deserves serious scientific scrutiny so we can learn its secrets.
An article published today in the British medical journal Nature reports that an international team of scientists have succeeded in decoding the entire genome of our favorite rodent. Prominent scientists working with the Alliance to identify research that would advance our understanding of the common denominator of disease--aging itself, have specifically called-out cross-species research studies using the naked mole rat as a powerful model that could lead the way to healthier aging for humans.
This means that this vital research is in full swing; and that an animal that is far from cute and cuddly might be man's best friend after all.
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I like mole rats too - not pretty, but pretty amazing, but I really like possums. I remember Alistair Cook in letter from America (I lived in England back then as a teenager), talking about mating behavior in some kind of vole or mouse. As an avid biologist I wondered why he was doing that when he almost always had a social message. He did, he was leading up to the role of apparently abstract or arcane research (that some people like to mock and block) in true discovery. His story led to the way this odd research resulted in better understanding of the endocrine system, and its role in therapeutics. Your story reminded me of that (heard it about 50 years ago, but it stuck in my head). Keep up the good work and best of luck with your business. I just left a successful (to me) science career (40 years is enough - I made the decision right in the middle of giving a keynote address to a small pathology society meeting at NIEHS a year ago; isn't that odd), and now I'm starting over in e-commerce as a neophyte (no sign of a somite yet, but just wait).
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