Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in people over the age of 65. Until relatively recently, people diagnosed with AMD faced an almost certain road of progressively worsening vision. For many, that road led to legal blindness. Thanks to new drugs, much of the vision loss from wet AMD can now be prevented—or at least slowed. In many cases, it can even be reversed.
These anti-VEGF (vascular endothelial growth factor) drugs target a protein that is involved in the growth of new blood vessels, reducing the leaking blood vessels that can damage the macula and cause vision loss. While there are a number of new therapies expected to reach the market soon, there are currently two available drugs that have been stealing the spotlight recently due to their vast difference in cost.
Lucentis is injected into the eye and has been found to stabilize vision in most patients, and restore it in around 40 percent. Avastin is another anti-VEGF injection that works similarly but is not yet approved by the FDA for the treatment of AMD (it is approved for the treatment of colorectal cancer). Because Avastin is significantly cheaper, many doctors prescribe Avastin off-label and a recent clinical trial found it to be as effective as Lucentis. The potential catch is that the safety trials are not yet finished, and there have been recent reports of serious eye infections in people using Avastin.
In addition to making a decision about what drug—if any—is right for them, patients diagnosed with AMD have a lot on their plate. In order to help them learn more about their disease and its treatment, the Alliance has updated and released its highly successful educational brochure—Taking a Closer Look at Age-Related Macular Degeneration. This is the 4th edition of the brochure and has been updated to reflect the latest advances in detection, prevention, and yes—treatment. It guides readers through the latest information on symptoms and risk factors, while offering ways to reduce risk. The widely used Amsler Grid can also still be found on the back cover.
More info on AMD is available at the Alliance’s AMD Health Corner.
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The disease is most common in people over age 60.
The retina is at the back of the eye. It changes light and images that enter the eye into nerve signals that are sent to the brain. A part of the retina called the macula makes vision sharper and more detailed.
seems to be a big issue, but I am sure that we will find a cure in the near future.
It is the first time when I read about this issue. Why just for people with over 60?
Any cure? when do you think that we can see updates?
Just call your doctor.
Lucentis is injected into the eye and has been found to stabilize vision in most patients, and restore it in around 40 percent. Avastin is another anti-VEGF injection that works similarly but is not yet approved by the FDA for the treatment of AMD (it is approved for the treatment of colorectal cancer).
Lucentis is injected into the eye and has been found to stabilize vision in most patients, and restore it in around 40 percent. Avastin is another anti-VEGF injection that works similarly but is not yet approved by the FDA for the treatment of AMD (it is approved for the treatment of colorectal cancer)
The cure is almost ready and I am sure that we will see imporvements in this domain.
I'm glad to see that there treatments to this terrible disease. To many people suffer.
Hopefully Avastin gets the FDA approval faster so that more people could afford this drug to combat Age-Related Macular Degeneration. Jack @ http://stickvacuumbest.com & http://uprightvacuumbest.com
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Avastin is another anti-VEGF injection that works similarly but is not yet approved by the FDA for the treatment of AMD (it is approved for the treatment of colorectal cancer).
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The growth of new blood vessels, reducing the leaking blood vessels that can damage the Macaulay and cause vision loss.I'm glad to see that there treatments to this terrible disease.
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It changes light and images that enter the eye into nerve signals that are sent to the brain. A part of the retina called the macula makes vision sharper and more detailed.
The potential catch is that the safety trials are not yet finished, and there have been recent reports of serious eye infections in people using Avastin.
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I am wondering if in 50 years time, the humans will have a longer life, if it's possible to leave 150 years or more? Or maybe our efforts are in vain.
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Avastin is another anti-VEGF injection that works similarly but is not yet approved by the FDA for the treatment of AMD (it is approved for the treatment of colorectal cancer). Because Avastin is significantly cheaper.
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