Return to top of page

Drug Pricing

The Alliance for Aging Research believes that all people should have access to high-quality healthcare. However, older adults and people with disabilities are increasingly exposed to high out-of-pocket (OOP) costs for medically-necessary medications. Research continues to show that increases in patients’ out-of-pocket costs lead to lower drug adherence, higher mortality, and increased overall healthcare costs. Policymakers must work to improve patient affordability.

However, not all proposals to address prescription drug prices are equal. Some proposals may actually harm older adults by restricting access to innovative cures or set drug prices using formulas that discriminate based on age or disability.

The Alliance for Aging Research is advocating for meaningful drug pricing reform through the following initiatives:

Addressing Older Adults’ Out-of-Pocket Drug Costs

The Alliance for Aging Research leads Project Lower Out of Pocket (LOOP). Project LOOP advocates for two policy changes to the Medicare Part D program to make prescription drugs more affordable for older adults. We are advocating for a cap in the drug benefit design for Part D plans that would set a ceiling on the total out-of-pocket costs a beneficiary would pay in a calendar year. Secondly, we are advocating for a “smoothing” mechanism in Part D that would allow patients to pay for their high-cost medication over a year over the course of the benefit year rather than all at once. Visit to learn more.

Related Alliance Resources:

Education on the Discriminatory and Harmful Patient Impacts of International Reference Pricing

International drug reference pricing models would base the prices paid by Medicare or Medicaid on those paid by other countries, most of whom have very different healthcare systems and value different outcomes than the U.S., and reduce access to innovative medical products on the market. Unfortunately, these reference countries often use discriminatory methodologies that limit coverage and access to new medical treatments for older adults and people with disabilities. The implementation of international reference pricing would mean that some patients and people with disabilities have diseases that are too expensive to receive care, and will likely result in healthcare rationing as it has in other countries.

The Department of Health and Human Services recently attempted to advance two international reference pricing models. The International Pricing Index (IPI) was first proposed by the U.S. Department of Health and Human Services in the fall of 2018 for Medicare Part B drugs, which was later revised and renamed the Most Favored Nation (MFN) model. The MFN would have set the price Medicare pays for prescription drugs in Part B (drugs administered in a physician’s office or hospital outpatient department) at the lowest price paid by a comparison group of to-be-named countries. Due to lack of opportunities for stakeholders to provide input – and likely harms to patients and care providers – multiple federal courts ordered the government to stop the implementation of the MFN in December 2020.

Related Alliance Resources:

Opposing Use of Pricing Recommendations from the Institute for Clinical and Economic Review in Medicare and Medicaid

ICER creates reports known as “cost-effectiveness analyses” or “value assessments” that estimate how much a new medical treatment should cost. The reports use metrics, including the quality-adjusted life year (QALY), that place a lower value on treatments for older adults and people with disabilities. These reports can persuade insurers to deny coverage for treatments for older adults and dissuade pharmaceutical companies from developing drugs for rare diseases or conditions such as Alzheimer’s disease. ICER’s is currently advocating for Medicare and states’ Medicaid programs to utilize these problematic reports for drug pricing and coverage determinations. Visit to learn more.

Related Alliance Resources:

Moderating Drug Price Increases

Older adults are all too familiar with having the price of their prescription medication increase from year-to-year. The reasons behind these price increases are complex, but the end result is higher out-of-pocket costs for patients. According to an analysis by the Kaiser Family Foundation, of the 2,879 reported brand-name and generic drugs covered by Medicare Part D plans, 60 percent had list price increases that exceeded the inflation rate between July 2016 and July 2017, which was 1.7 percent. When the list price of a drug increases over a short duration of time beneficiaries will have to pay more for their medications through cost-sharing. Previous policies in the Medicaid program required manufacturers to issue an additional rebate when average manufacturer prices for a drug increase faster than inflation, as measured by the Consumer Price Index for All Urban Consumers (CPI-U). The Alliance for Aging Research supports an inflationary cap as one of several effective tools to help stabilize patients’ Part D prescription drug costs.

The Alliance for Aging Research partners with organizations to advance patient-centered drug pricing reform. Additional information can be found on the How We’re Funded page.

The Healthy Aging Blog on

Drug Pricing

Drug Pricing News & Updates

Living Longer and Loving It

Sign up for our monthly e-mail newsletter for the latest information on
scientific research on aging and health.

Ways to Give

There are many ways you can help accelerate the pace of scientific discoveries and their application to vastly improve the universal human experience of aging and health:

Platinum Transparency 2024 logo

The Alliance for Aging Research is a proud recipient of Candid’s Platinum Seal of Transparency.

Charity Navigator Four-Star Rating Badge

The Alliance for Aging Research is proud to be rated a 4-star charity by Charity Navigator.