Founded in 2005, the Accelerate Cure/Treatments for All Dementias (ACT-AD) Coalition is a group of more than 50 national nonprofit organizations, chaired by the Alliance for Aging Research, urgently working to speed up the development of potential cures and more effective treatments for all dementias.
Alzheimer’s Disease PCORI Priorities Letter
Published January 5, 2016
The Alliance for Aging Research submitted a letter to the Patient-Centered Outcomes Research Institute (PCORI) suggesting possible research for the Institute to consider, aimed at improving outcomes for people with Alzheimer’s disease. The Alliance encouraged the following topics:
- Impact of non-pharmacologic interventions for Alzheimer’s disease on patient outcomes, caregiver burden and rates of institutionalization
- Evaluation of screening methodologies, for relative ease/uptake and associated optimization across provider groups and settings of care;
- Assessment of how Alzheimer’s disease diagnosis and treatment affects management of comorbidities;
- Frequency of emergency room visits for Alzheimer’s disease patients and identification of best practices for potential mitigation;
- Comparisons of currently available tools used to assess cognition to identify which is most effective for specific populations; and
- Impact of knowing positive ApoE genotype status on patient, caregiver, and provider behaviors/outcomes as compared to ApoE negative status.