The Alliance for Aging Research submitted comments to the Centers for Medicare and Medicaid Services (CMS) on its proposed rule: CMS-3295-P, Medicare and Medicaid Programs; Hospital and Critical Access Hospital (CAH) Changes to Promote Innovation, Flexibility, and Improvement in Patient Care. The Alliance’s comments focused on quality assessment and reporting, antibiotic stewardship requirements, and infection prevention standards in the proposed rule that advance the priorities of the National Action Plan for Combating Antibiotic-Resistant Bacteria (CARB).